Ultrastructure of the normal atrial endocardium.

Recurrent sustained ventricular tachycardia: structure and ultrastructure of subendocardial regions in which tachycardia originates.

Surgical resection of the endocardium and subendocardium often abolishes chronic recurrent sustained ventricular tachycardia in patients with healed myocardial infarcts or ventricular aneurysms, presumably by interrupting the reentrant pathway. To define the morphologic characteristics of cells in the reentrant pathway, we studied the histology and ultrastructure of the endocardial resections o...

Thrombomodulin and tissue factor pathway inhibitor in endocardium of rapidly paced rat atria.

BACKGROUND Atrial fibrillation (AF) is well known as one of the cardiogenic causes for thromboembolism. Although decreased flow and hypercoagulable state of the blood in the fibrillating atrium have been emphasized as the underlying mechanisms, endocardial dysfunction in maintaining the local coagulation balance could also contribute to the thrombogenesis in AF. METHODS AND RESULTS The paroxy...

Underlying Heart Disease Shortening of AERP Transient elevation of Atrial Natriuretic Peptides Mild changes in atrial ultrastructure Prolongation of AERP Atrial dilatation Chronic elevation of Atrial Natriuretic Peptides Atrial fibrosis Degenerative changes in atrial ultrastructure

The Effect of Amiodarone on the Ultrastructure of Ganglionic Neurons of Rabbit Heart

Purpose: This research has been carried out to study the morphological and ultrastructural changes of rabbit heart ganglionic neurons and nerve fibers after treatment with Amiodarone. Materials and Methods: 21 rabbits were divided into control and two experimental groups. The first experimental group for one week and the second experimental group for two weeks were injected intraperitoneally 8...

Heterogeneous atrial wall thickness and stretch promote scroll waves anchoring during atrial fibrillation.

AIMS Atrial dilatation and myocardial stretch are strongly associated with atrial fibrillation (AF). However, the mechanisms by which the three-dimensional (3D) atrial architecture and heterogeneous stretch contribute to AF perpetuation are incompletely understood. We compared AF dynamics during stretch-related AF (pressure: 12 cmH(2)O) in normal sheep hearts (n = 5) and in persistent AF (PtAF,...